177+ Rental Villas and Private Getaways in Otay Mesa West |
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Otay Mesa West Villa Rentals

About Otay Mesa West Vacation Rentals

There are more than 177 incredible getaway rentals that are available in Otay Mesa West. These choices include villas, hotels, and other rental options. Browse from a massive selection of luxury amenities at great prices, providing you with the dream spot to base your next vacation. Relax with BedroomVillas and uncover great stays in Otay Mesa West.

BedroomVillas features numerous last-minute deals on villas, hotels, and rentals, in locations near you or across the globe. If you need a place for a group or event, be it a hotel or vacation rental (as well as cabins and private luxury villas), let us help. With BedroomVillas in Otay Mesa West, you can compare options from multiple suppliers with a single click to find the price point, amenities, and style of stay that works for you. Group deals, private pools, hot tubs, allows pets, or even huge master suite bedrooms with open-air showers? You can find it all with the BedroomVillas vacation rentals, resorts, and Airbnb-style properties in Otay Mesa West. Places to stay near Otay Mesa West are 627.35 ft² on average, with prices averaging CA $459 a night.

BedroomVillas helps you find the ideal holiday rental to create lifetime travel memories in Otay Mesa West. Prices listed are often found to be discounted versus the rack rates. Just search for your destination and secure your perfect place to stay today.

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Top Private Villas, Resorts, and Rentals in Otay Mesa West

Type Count
Vacation Homes 118
Holiday Apartments 23
Cottages 2

Use these Quick Filters to Find a Vacation Rental in Otay Mesa West

★ Pro Tip: BedroomVillas is a luxury vacation rental website, pulling some of the top private villas and exclusive holiday stays from sources across the web. We supply you with a huge list of incredible beach houses and holiday rentals from trusted, reliable suppliers, helping you to compare prices and locations to find the best fit for your getaway. Create lifelong memories in Otay Mesa West with BedroomVillas.

Weather in Otay Mesa West, CA

View the weather forecast for Otay Mesa West before booking your Otay Mesa West Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Frequently Asked Questions About Otay Mesa West?

What are the top hotels or resorts in Otay Mesa West?

We provide an array of great vacation destinations in Otay Mesa West. If you are looking to stay in or around the Otay Mesa West area, make sure to browse our options to find a premium rental location in a top vacation destination. Whether it is a few nights, a week, or more, we've got the luxury stays that rank among the Top Vacation Rentals in Otay Mesa West:

How many vacation rentals have private pools in Otay Mesa West?

We have 9 luxury villas and vacation rentals featuriung a private pool in and near Otay Mesa West. Some of the best destinations to stay that feature or have access to a swimming pool are:

Which hotel or resort in Otay Mesa West is best for families?

Searching for a family-friendly getaway in Otay Mesa West? We've got you covered. Check out one of these luxurious getaways that are highly-rated and perfect fits for families of all sizes.

How many hotels, resorts, or rentals are available in Otay Mesa West?

BedroomVillas offers a consistent supply of new options, combined with established great stays in top areas. Currently, the number of properties listed by BedroomVillas in 2025 is over 177 in the Otay Mesa West area, and that number rises every day. By combining listings from multiple websites and travel providers, BedroomVillas can provide you with a diverse amount of choices of the best luxury stays in Otay Mesa West. 

Nearby Neighborhood (4) 
Neighborhood Property Count
Ocean View Hills Rental Villas and Private Getaways in San Diego, California 110
Nestor Rental Villas and Private Getaways in San Diego, California 315
Otay Rental Villas and Private Getaways in San Diego, California 247
Palm City Rental Villas and Private Getaways in San Diego, California 355

People Also Ask

There are 22 hotels in Otay Mesa West and 141 rentals

Recently Booked Hotels, Resorts, or Rentals in Otay Mesa West